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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1840957Generated: October 30, 2026

7-Methylindole → 7-Methyl-3-(4-piperidinyl)-1H-indole

https://huagongshe.com/reaction/1840957

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-MethylindoleHCID 70275—
ReactantPiperonylamineHCID 2723901—
Product7-Methyl-3-(4-piperidinyl)-1H-indoleHCID 11298855—

Reaction Steps

This compound was prepared following the procedure described in Example 1 (parts A and B) starting with 1 g (7.6 mmol) of 7-methylindol and 2.9 g (19 mmol) of 4-piperidone monohydrate hydrochloride. After the usual work-up 0.8 g (50% of yield) of the desired product were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06683096B2
Source datasetuspto-grants-2004_01
ORD IDord-6e196de14eba4c729f7a9cc0d7ee4ccf
Source noteuspto-grants-2004_01