Potassium Iodide → HCID 23444836, compound

HRID 1840969Notes

Reaction equation

HRID 1840969 reaction equation
[CH2:1]([O:3][CH2:4][CH2:5][N:6]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8]([CH:15]2[CH2:20][CH2:19][NH:18][CH2:17][CH2:16]2)=[CH:7]1)[CH3:2].C[O:22][C:23](=[O:39])[C:24]([C:27]1[CH:32]=[CH:31][C:30]([C:33](=[O:38])[CH2:34][CH2:35][CH2:36]Cl)=[CH:29][CH:28]=1)([CH3:26])[CH3:25].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>>[CH2:1]([O:3][CH2:4][CH2:5][N:6]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[C:8]([CH:15]2[CH2:16][CH2:17][N:18]([CH2:36][CH2:35][CH2:34][C:33]([C:30]3[CH:31]=[CH:32][C:27]([C:24]([CH3:25])([CH3:26])[C:23]([OH:39])=[O:22])=[CH:28][CH:29]=3)=[O:38])[CH2:19][CH2:20]2)=[CH:7]1)[CH3:2]

Participants

5

Reactant 4

HCID 4875Potassium IodideHCID 11430Potassium CarbonateHCID 99036001-(2-ethoxyethyl)-3-piperidin-4-yl-1H-indoleHCID 10062338Methyl 4-(4-chloro-1-oxobutyl)-alpha,alpha-dimethylbenzeneacetate

Product 1

HCID 23444836HCID 23444836, compound

Procedure

This compound was prepared following the procedure described in Example 152 (parts D and E) starting with 0.1 g (0.37 mmol) of 1-(2-ethoxyethyl)-3-piperidin-4-yl-1H-indole, 0.142 g (0.48 mmol) of 2-[4-(4-chlorobutyryl)-phenyl]-2-methyl-propionic acid methyl ester, 0.07 g (0.48 mmol) of potassium carbonate and 0.04 g (0.24 mmol) of potassium iodide.

Workup

  1. customThis compound was prepared

Sources & evidence

ORD record
ord-87ca407f76684c3e8ef5346b68bd7ccd
Source dataset
uspto-grants-2004_01
Patent number
US06683096B2

Reaction notes

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