Acetic Acid → HCID 23445087, compound

HRID 1841271Notes

Reaction equation

HRID 1841271 reaction equation
[F:1][C:2]([F:12])([F:11])[S:3][C:4]1[CH:10]=[CH:9][C:7]([NH2:8])=[CH:6][CH:5]=1.[CH:13](OCC)(OCC)OCC.[N+:23]([CH2:26]C(OCC)=O)([O-])=O.[C:32]([OH:35])(=[O:34])[CH3:33]>[Fe]>[F:12][C:2]([S:3][C:4]1[CH:10]=[CH:9][C:7]([N:8]2[CH:13]=[C:33]([C:32]([OH:35])=[O:34])[N:23]=[CH:26]2)=[CH:6][CH:5]=1)([F:11])[F:1]

Participants

6

Reactant 4

HCID 176Acetic Acid2×HCID 31214Ethyl orthoformate2×HCID 69379Ethyl nitroacetateHCID 1230544-((Trifluoromethyl)thio)aniline

Product 1

HCID 23445087HCID 23445087, compound

Reagents, catalysts & solvents 1

HCID 23925IronCatalyst

Procedure

Following the general method described in example 234, 4-(trifluoromethylthio)aniline was reacted with triethyl orthoformate, ethyl nitroacetate and acetic acid followed by treatment with triethyl orthoformate, iron and acetic acid and subsequent alkaline hydrolysis. The title compound was obtained as a light brown crystalline solid. Mp. 247-248° C. (H2O/dioxane), MS: m/e=288 (M+).

Sources & evidence

ORD record
ord-c5fe0a77c6f94f3a87f69dae4e29c0b1
Source dataset
uspto-grants-2004_01
Patent number
US06683097B2

Reaction notes

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