Methanol → 3-Amino-1-(3-(trifluoromethyl)-5,6-dihydro(1,2,4)triazolo(4,3-a)pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one
Reaction equation
[CH3:38][OH:39].[F:1][C:2]([F:3])([F:4])[C:33]([NH:5][CH:6]([CH2:7][c:8]1[c:9]([F:16])[cH:10][c:11]([F:15])[c:12]([F:14])[cH:13]1)[CH2:17][C:18]([N:19]1[CH2:20][c:21]2[n:22]([c:25]([C:28]([F:29])([F:30])[F:31])[n:26][n:27]2)[CH2:23][CH2:24]1)=[O:32])=[O:34].[Li+:37].[OH-:36].[OH2:35].[OH2:40]>>[NH2:5][CH:6]([CH2:7][c:8]1[c:9]([F:16])[cH:10][c:11]([F:15])[c:12]([F:14])[cH:13]1)[CH2:17][C:18]([N:19]1[CH2:20][c:21]2[n:22]([c:25]([C:28]([F:29])([F:30])[F:31])[n:26][n:27]2)[CH2:23][CH2:24]1)=[O:32]Participants
6
Sources & evidence
- ORD record
- ord-f200cdf8dc474fe6b8898417ef604e62
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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