反应详情

温度

60 °C

Aluminium trichloride (5.1 g, 3.18 mmol) was added to a suspension of 2,6-bis(chlorocarbonyl)pyridine (3.7 g, 18 mmol) in 200 ml of benzene. The reaction mixture was heated to 60° C. and kept at that temperature for 4 h and subsequently for 16 h at room temperature. The mixture was poured into water, the organic layer was separated and evaporated to dryness. The residue was dissolved in CH2Cl2 and filtered. Removal of CH2Cl2 in vacuum yielded 3.0 g (58%) of product.

1. customthe organic layer was separated
2. customevaporated to dryness
3. dissolutionThe residue was dissolved in CH2Cl2
4. filtrationfiltered
5. customRemoval of CH2Cl2 in vacuum