1,4-Dibromobutane → [4-(4-Bromo-butoxy)-phenyl]-carbamic acid tert-butyl ester

HRID 1841587Notes

Reaction equation

HRID 1841587 reaction equation
[C:1]([O:5][C:6](=[O:15])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([OH:14])=[CH:10][CH:9]=1)([CH3:4])([CH3:3])[CH3:2].[Br:16][CH2:17][CH2:18][CH2:19][CH2:20]Br>>[C:1]([O:5][C:6](=[O:15])[NH:7][C:8]1[CH:9]=[CH:10][C:11]([O:14][CH2:20][CH2:19][CH2:18][CH2:17][Br:16])=[CH:12][CH:13]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 80561,4-DibromobutaneHCID 2756771N-Boc-4-hydroxyaniline

Product 1

HCID 68615222[4-(4-Bromo-butoxy)-phenyl]-carbamic acid tert-butyl ester

Procedure

In analogy to example 1.4, reaction of (4-Hydroxy-phenyl)-carbamic acid tert-butyl ester with 1,4-dibromobutane yielded [4-(4-Bromo-butoxy)-phenyl]-carbamic acid tert-butyl ester, MS: 344 (MH+, 1Br).

Sources & evidence

ORD record
ord-8c39cbd9c4cb450ba2fc4748696ef333
Source dataset
uspto-grants-2004_01
Patent number
US06683201B2

Reaction notes

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