2-Bromopropane → HCID 178505971, compound

Participants

Reaction Steps

Air inside a reaction vessel of the same kind as the one used in Example 13 is displaced by a nitrogen gas in a satisfactory manner. Then, 2.025 g (0.083 mole) of magnesium, 13.198 g (0.079 mole) of pentafluorobenzene, and 20 ml of tetrahydrofuran (THF) serving as the solvent (e) (ether solvent (e)) are charged to the reaction vessel. Also, 10.782 g (0.083 mole) of isopropyl bromide is charged to the dropping funnel. Next, isopropyl bromide is dropped to the above contents with stirring under a nitrogen gas flow. After the completion of the dropping, the resulting reaction solution is subject to reaction for 2 hours at 57.0° C. with stirring. Consequently, pentafluorophenyl magnesium bromide is obtained in the form of a THF solution. A reaction yield of pentafluorophenyl magnesium bromide found in the same manner as Example 13 is 82.9 percent by mole.

Provenance & Evidence