Trifluoroacetic acid → HCID 52938413, compound

Participants

Reaction Steps

To a solution of [1-(4-Acryloylamino-benzenesulfonyl)-piperidin-4-yl]-carbamic acid tert-butyl ester (0.57 g, 1.4 mmol) in DCM (10 ml) was added trifluoroacetic acid (10 ml) in one portion. The resulting mixture was then stirred at room temperature under a nitrogen atmosphere for 3 hours. After this time the reaction was concentrated under vacuum to afford the title compound (0.40 g, 93% yield) as an orange solid.

Provenance & Evidence