Trifluoroacetic acid → HCID 67193956, compound

Participants

Reaction Steps

To a solution of 4-(4-Acryloylamino-2-methoxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester (2.0 g, 4.7 mmol) in DCM (20 ml) was added trifluoroacetic acid (5 ml) in one portion. The resulting mixture was then stirred at room temperature under a nitrogen atmosphere for 3 hours. After this time the reaction was concentrated under vacuum to afford the title compound (1.3 g, 93% yield) as an orange gum.

Provenance & Evidence