Thionyl Chloride → HCID 86682849, compound

Participants

Reaction Conditions

Reaction Steps

Thionyl chloride (4.0 ml, 55.0 mmol) was added dropwise to a stirred solution of 1-(4-nitro-benzenesulfonyl)-piperidine-4-carboxylic acid (1.25 g, 3.98 mmol) in toluene (12 ml) and the mixture was heated at 80° C. for 2 hours. After this time, the reaction mixture was concentrated under vacuum to afford the title compound as a white solid which was used without further purification.

Provenance & Evidence