HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-piperidineacetate → {1-[(S)-4-(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperidin-4-yl}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-piperidineacetate | HCID 1515259 | — |
| Reactant | 1-[(S)-4-(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperidine-4-carboxylic acid | HCID 68359044 | — |
| Reactant | 4-[(S)-4-(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperazine-1-carboxylic acid tert-butyl ester | HCID 86695362 | — |
| Product | {1-[(S)-4-(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-3-yl)-benzyl]-piperidin-4-yl}-acetic acid | HCID 86695359 | — |
Reaction Steps
The title product GG is prepared from compound GG-1 (prepared from Intermediate C and piperidin-4-yl-acetic acid methyl ester according to General Method F) according to the procedure used to synthesize Intermediate K.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946203B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-25a6da96c342439fbb882debd520d210 |
| Source note | uspto-grants-2015_02 |