Tetrabutylammonium Fluoride → HCID 57827681, compound

HRID 1842222Notes

Reaction equation

HRID 1842222 reaction equation
[F-].C([N+](CCCC)(CCCC)CCCC)CCC.C([Si]([O:36][CH2:37][CH2:38][CH:39]([O:43][CH2:44][CH3:45])[CH2:40][CH:41]=[CH2:42])(C1C=CC=CC=1)C1C=CC=CC=1)(C)(C)C>C1COCC1>[CH2:44]([O:43][CH:39]([CH2:40][CH:41]=[CH2:42])[CH2:38][CH2:37][OH:36])[CH3:45]

Participants

4

Reactant 2

HCID 2724141Tetrabutylammonium FluorideHCID 57827623HCID 57827623, compound

Product 1

HCID 57827681HCID 57827681, compoundYield 71.2%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Tetrabutylammonium fluoride (1 M solution in THF, 13 mL) was added to a solution of tert-butyl-(3-ethoxy-5-hexenyloxy)diphenylsilane (4.1 g) in THF (40 mL) at room temperature, followed by stirring for one hour. The reaction solution was concentrated. The resulting crude product was purified by silica gel column chromatography to obtain the title compound (1.1 g).

Workup

  1. concentrationThe reaction solution was concentrated
  2. customThe resulting crude product was purified by silica gel column chromatography

Sources & evidence

ORD record
ord-2dc30cff1f6644c9900461a93550997f
Source dataset
uspto-grants-2015_02
Patent number
US08946210B2

Reaction notes

Loading…