Sodium ion → N-(6-formyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-3-[methyl-(3-trifluoromethyl-benzenesulfonyl)-amino]-3-phenyl-propionamide

HRID 184227Notes

Reaction equation

HRID 184227 reaction equation
[CH3:44][I:45].[CH:1](=[O:2])[c:3]1[cH:4][c:5]2[c:10]([cH:11][cH:12]1)[CH:9]([NH:13][C:14]([CH2:15][CH:16]([NH:17][S:18](=[O:19])(=[O:20])[c:21]1[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]1)[c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1)=[O:37])[CH2:8][CH2:7][CH2:6]2.[Na+:38].[Na+:39].[O-:40][C:41](=[O:42])[O-:43].[O:46]=[CH:47][N:48]([CH3:49])[CH3:50]>>[CH:1](=[O:2])[c:3]1[cH:4][c:5]2[c:10]([cH:11][cH:12]1)[CH:9]([NH:13][C:14]([CH2:15][CH:16]([N:17]([S:18](=[O:19])(=[O:20])[c:21]1[cH:22][c:23]([C:27]([F:28])([F:29])[F:30])[cH:24][cH:25][cH:26]1)[CH3:41])[c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1)=[O:37])[CH2:8][CH2:7][CH2:6]2

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 6328Methyl iodideHCID 19660Carbonate IonHCID 86598510N-(6-formyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-3-phenyl-3-(3-trifluoromethyl-benzenesulfonylamino)-propionamide

Product 1

HCID 86598509N-(6-formyl-1,2,3,4-tetrahydro-naphthalen-1-yl)-3-[methyl-(3-trifluoromethyl-benzenesulfonyl)-amino]-3-phenyl-propionamide

Sources & evidence

ORD record
ord-e82e668dda8743dd9d8882c436e4a435
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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