Hydrochloric Acid → HCID 178509513, compound

Participants

Reaction Steps

The 3-(5-cyano-1H-benzoimidazol-2-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester (9 g, 28.8 mmol) in a solution of 4M HCl in MeOH (50 mL) was stirred at 60° C. for 1 h, then it was concentrated to give the crude product (8 g, 79%). The crude product was used in the next step without further purification.

Provenance & Evidence