Hydrazine → HCID 178454835, compound

HRID 1842570Notes

Reaction equation

HRID 1842570 reaction equation
[Si:1]([O:8][CH:9]([CH:27]([CH3:29])[CH3:28])[C:10](=O)/[C:11](=[CH:22]/[N:23](C)C)/[C:12]([O:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[O:13])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[NH2:30]N>C(O)C>[Si:1]([O:8][CH:9]([C:10]1[C:11]([C:12]([O:14][CH2:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[O:13])=[CH:22][NH:23][N:30]=1)[CH:27]([CH3:29])[CH3:28])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 58059659HCID 58059659, compound

Product 1

HCID 178454835HCID 178454835, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To a solution of benzyl (2Z)-4-{[tert-butyl(dimethyl)silyl]oxy}-2-[(dimethylamino)methylene]-5-methyl-3-oxohexanoate (0.13 g, 0.31 mmol) in ethanol (3.1 mL) was added hydrazine (0.28 mL, 3.1 mmol). The mixture was stirred at ambient temperature. After 30 min, the mixture was concentrated to dryness and taken into the next reaction. MS 389.1 (M+1).

Workup

  1. concentrationthe mixture was concentrated to dryness
  2. customtaken into the next reaction

Sources & evidence

ORD record
ord-af593c4eaae1413485cad3402ef404ae
Source dataset
uspto-grants-2015_02
Patent number
US08946231B2

Reaction notes

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