HCID 70816329, compound → HCID 64768098, compound

Participants

Reaction Steps

To a stirred solution of 2-fluoro-1-((2-methoxyethoxy)methyl)-4-nitrobenzene (4.0 g, 1.0 eq) in THF (50 mL) was added 10% Pd—C and the reaction mixture was stirred under H2 gas balloon at for 16 h. The reaction mixture was passed through celite pad and the solvent evaporated to get 3-fluoro-4-((2-methoxyethoxy)methyl)aniline (2.50 g, 72%) as solid (TLC system: EtOAc/PE (1:1), Rf: 0.3).

Provenance & Evidence