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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 184321Generated: October 27, 2026

Sodium ion → tert-Butyl 4-(1-(3-fluoro-2-pivalamidophenyl)-1-hydroxy-3-methoxy-3-oxopropan-2-yl)piperidine-1-carboxylate

https://huagongshe.com/reaction/184321

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantDiisopropylamineHCID 7912—
ReactantTetrahydrofuranHCID 8028—
ReactantCyclohexaneHCID 8078—
ReactantHydrideHCID 166653—
Reactanttert-Butyl 4-(2-methoxy-2-oxoethyl)piperidine-1-carboxylateHCID 1514280—
ReactantN-(2-Fluoro-6-formylphenyl)pivalamideHCID 59424313—
ReactantButyllithiumHCID 178418339—
Producttert-Butyl 4-(1-(3-fluoro-2-pivalamidophenyl)-1-hydroxy-3-methoxy-3-oxopropan-2-yl)piperidine-1-carboxylateHCID 59424341—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-75d10b285269436cbc265db1b5cab9fa
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)