Sodium ion → tert-Butyl 4-(1-(3-fluoro-2-pivalamidophenyl)-1-hydroxy-3-methoxy-3-oxopropan-2-yl)piperidine-1-carboxylate
Reaction equation
[CH2:13]1[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18]1.[CH3:19][O:20][C:21]([CH2:22][CH:23]1[CH2:24][CH2:25][N:26]([C:29](=[O:30])[O:31][C:32]([CH3:33])([CH3:34])[CH3:35])[CH2:27][CH2:28]1)=[O:36].[CH:1]([NH:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[F:39][c:40]1[c:41]([NH:48][C:49]([C:50]([CH3:51])([CH3:52])[CH3:53])=[O:54])[c:42]([CH:46]=[O:47])[cH:43][cH:44][cH:45]1.[H-:37].[Li:8][CH2:9][CH2:10][CH2:11][CH3:12].[Na+:38].[O:55]1[CH2:56][CH2:57][CH2:58][CH2:59]1>>[CH3:19][O:20][C:21]([CH:22]([CH:23]1[CH2:24][CH2:25][N:26]([C:29](=[O:30])[O:31][C:32]([CH3:33])([CH3:34])[CH3:35])[CH2:27][CH2:28]1)[CH:46]([c:42]1[c:41]([NH:48][C:49]([C:50]([CH3:51])([CH3:52])[CH3:53])=[O:54])[c:40]([F:39])[cH:45][cH:44][cH:43]1)[OH:47])=[O:36]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-75d10b285269436cbc265db1b5cab9fa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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