反应详情

100 mg (0.26 mmol) of 4-[1-(4-methoxybenzyl)-3-(3-nitrophenyl)-1H-pyrazol-4-yl]-pyridine were dissolved in 3 mL of dichloromethane and 80 mg (0.52 mmol) of m-chloroperbenzoic acid were added. The mixture was stirred at room temperature for 4 hours, diluted with the same solvent and washed with aqueous sodium hydrogenocarbonate. The organic layer was then dried over sodium sulphate and evaporated to afford, after crystallization from ethylacetate, 49 mg (47%) of the title compound.

1. additiondiluted with the same solvent
2. washwashed with aqueous sodium hydrogenocarbonate
3. dry with materialThe organic layer was then dried over sodium sulphate
4. customevaporated
5. customto afford
6. customafter crystallization from ethylacetate, 49 mg (47%) of the title compound