HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine, hydrofluoride (1:1) → HCID 66705837, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine, hydrofluoride (1:1) | HCID 64774 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Reactant | 3,5-DibroMo-4-chloro-pyridin-2-ylaMine | HCID 66705914 | — |
| Product | HCID 66705837 | HCID 66705837 | 83% |
Reaction Steps
The reaction and post-treatment were carried out according to Example (8a) using 3,5-dibromo-4-chloropyridin-2-amine produced in Example (14a) (10.1 g, 35.4 mmol), sodium nitrite (3.66 g, 53.1 mmol) and hydrogen fluoride-pyridine (50 mL) to obtain the title compound (8.50 g, 83%) as a pale yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946264B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-44971ca8e29b4ac190f89b48945cd083 |
| Source note | uspto-grants-2015_02 |