HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 66705731, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Methyl 3-[[6-[(3,5-dibromo-4-chloro-2-pyridinyl)oxy]-1-methyl-1H-benzimidazol-2-yl]methoxy]benzoate | HCID 66705777 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66705731 | HCID 66705731 | 8.4% |
Reaction Steps
The reaction and post-treatment were carried out according to Example (3b) using methyl 3-({6-[(3,5-dibromo-4-chloropyridin-2-yl)oxy]-1-methyl-1H-benzimidazol-2-yl}methoxy)benzoate produced in Example (14c) (1.56 g, 2.68 mmol), sodium methoxide (5.0 M solution in methanol, 5.36 mL, 26.8 mmol), water (5 mL) and methanol (100 mL) to obtain the title compound (0.13 g, 8%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946264B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-ed176af7a4b94b0b8ac8adc5d3a5b2cd |
| Source note | uspto-grants-2015_02 |