Methyl 3-[2-({4-[(2-methoxy-6-methylpyridin-4-yl)oxy]-2-(methylamino)phenyl}amino)-2-oxoethoxy]benzoate → Methyl 3-({6-[(2-Methoxy-6-methylpyridin-4-yl)oxy]-1-methyl-1H-benzimidazol-2-yl}methoxy)benzoate

Participants

Reaction Steps

The reaction and post-treatment were carried out according to Example (16f) using methyl 3-[2-({4-[(2-methoxy-6-methylpyridin-4-yl)oxy]-2-(methylamino)phenyl}amino)-2-oxoethoxy]benzoate produced in Example (17d) (4.44 g, 9.83 mmol) and acetic acid (50 mL) to obtain the title compound (4.12 g, 99%) as a white powder.

Provenance & Evidence