HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 86661629, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 2-Chloro-5-hydroxypyridine | HCID 819821 | — |
| Reactant | tert-Butyl [(5-chloro-2-nitrophenyl)methyl]carbamate | HCID 71357443 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | HCID 86661629 | HCID 86661629 | — |
Reaction Steps
The reaction and post-treatment were carried out according to Example (1a) using 6-chloropyridin-3-ol (10 g, 77 mmol), tert-butyl (5-chloro-2-nitrophenyl)methylcarbamate (19 g, 66 mmol), sodium hydride (56%, 3.1 g, 77 mmol) and N-methylpyrrolidinone (80 mL) to obtain the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946264B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-08cdb804906c44ac9755f600e63f9eb1 |
| Source note | uspto-grants-2015_02 |