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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1843886Generated: November 2, 2026

HCID 66801648, compound → HCID 66803579, compound

https://huagongshe.com/reaction/1843886

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66801648HCID 66801648—
CatalystPalladiumHCID 23938—
SolventAcetic AcidHCID 176—
SolventMethanolHCID 887—
ProductHCID 66803579HCID 66803579—

Reaction Steps

Using analogous reaction conditions as described in Example 24, 2-(4-methyl-pyridin-3-yl)-7-nitro-2H-isoquinolin-1-one (I-24b: 120 mg, 0.4240 mmol) in methanol (10 mL) and acetic acid (0.1 mL) was reduced using Pd/C (40 mg) at 50 PSI in a Parr hydrogenator at room temperature for 3.30 hours.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08946260B2
Source datasetuspto-grants-2015_02
ORD IDord-fff20d3b79af4f10b655bf50d8bc80cd
Source noteuspto-grants-2015_02