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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1843897Generated: October 31, 2026

HCID 66804016, compound → HCID 66803579, compound

https://huagongshe.com/reaction/1843897

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 66804016HCID 66804016—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 66803579HCID 6680357982.02%

Reaction Steps

Using analogous reaction conditions as described in Example 25, 2-(4-methyl-pyridin-3-yl)-7-nitro-3,4-dihydro-2H-isoquinolin-1-one (I-30a: 150 mg, 0.53 mmol) in methanol (100 mL) was reacted with 10% Pd/C (30 mg) to afford 110 mg of the product (82.02% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08946260B2
Source datasetuspto-grants-2015_02
ORD IDord-97742715fb084b5892b538b5589cfe89
Source noteuspto-grants-2015_02