Potassium Nitrate → HCID 89963686, compound

HRID 1844025Notes

Reaction equation

HRID 1844025 reaction equation
[CH3:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[C:8](=[O:12])[N:7]([C:13]1[CH:14]=[N:15][CH:16]=[CH:17][C:18]=1[CH3:19])[CH2:6][CH2:5]2.[N+:20]([O-])([O-:22])=[O:21].[K+]>OS(O)(=O)=O>[CH3:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[N+:20]([O-:22])=[O:21])[C:8](=[O:12])[N:7]([C:13]1[CH:14]=[N:15][CH:16]=[CH:17][C:18]=1[CH3:19])[CH2:6][CH2:5]2

Participants

4

Reactant 2

HCID 24434Potassium NitrateHCID 89964092HCID 89964092, compound

Product 1

HCID 89963686HCID 89963686, compoundYield 80.3%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

6-Methyl-2-(4-methylpyridin-3-yl)-3,4-dihydroisoquinolin-1(2H)-one (I-69e: 1 g, 3.953 mmol) in conc. H2SO4 (11.9 mL) was reacted with KNO3 (439 mg, 4.348 mmol) to afford 940 mg of the product (80.3% yield).

Sources & evidence

ORD record
ord-75b75a12f4b644f7b195e85c007107aa
Source dataset
uspto-grants-2015_02
Patent number
US08946260B2

Reaction notes

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