HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → HCID 89964173, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Potassium Nitrate | HCID 24434 | — |
| Reactant | HCID 89964166 | HCID 89964166 | — |
| Product | HCID 89964173 | HCID 89964173 | 68% |
Reaction Steps
6-Methyl-2-(4-(trifluoromethyl)pyridin-3-yl)-3,4-dihydroisoquinolin-1(2H)-one (71A: 450 mg, 1.465 mmol) was reacted with concentrated H2SO4 (4.4 mL) and KNO3 (163 mg, 1.6126 mmol) for 2 hours to afford 350 mg of the product (68% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946260B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-c0aab4cf98c84d118713c96633ece227 |
| Source note | uspto-grants-2015_02 |