Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitromethane | HCID 6375 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 4-Chloro-3-methoxybenzaldehyde | HCID 12909725 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 66802111 | HCID 66802111 | 66.6% |
Reaction Steps
4-Chloro-3-methoxybenzaldehyde (1 g, 5.88 mmol) in ethanol (10 mL) was reacted with nitro methane (358 mg, 5.88 mmol) and 10N NaOH (0.6 mL, 28.11 mmol). The resulting mixture was stirred at 0° C. for 3 hours to afford 800 mg of the product (66.6% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08946260B2 |
|---|
| Source dataset | uspto-grants-2015_02 |
|---|
| ORD ID | ord-6f2a8dcdd4264326b87fc2a6f50ba820 |
|---|
| Source note | uspto-grants-2015_02 |
|---|
