Pyrrolidine → 6-Bromo-2-(3-methoxy-pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridine

HRID 1844480노트

반응식

HRID 1844480 반응식
N1CCC[CH2:2]1.[Br:6][C:7]1[CH:8]=[CH:9][C:10]2[N:11]([N:13]=[C:14]([N:16]3[CH2:21][CH2:20][O:19][CH2:18][CH2:17]3)[N:15]=2)[CH:12]=1>>[Br:6][C:7]1[CH:8]=[CH:9][C:10]2[N:11]([N:13]=[C:14]([N:16]3[CH2:17][CH2:2][CH:20]([O:19][CH3:18])[CH2:21]3)[N:15]=2)[CH:12]=1

참가 물질

3

반응물 2

HCID 31268PyrrolidineHCID 717438774-(6-Bromo-[1,2,4]triazolo[1,5-A]pyridin-2-YL)morpholine

생성물 1

HCID 894645726-Bromo-2-(3-methoxy-pyrrolidin-1-yl)-[1,2,4]triazolo[1,5-a]pyridine

실험 절차

Using pyrrolidine, this compound was prepared following the same method as for the synthesis of 6-bromo-2-morpholin-4-yl-[1,2,4]triazolo[1,5-a]pyridine Brown solid (2.5 g, 47%). MS: m/z=298 (M+H+).

후처리

  1. customthis compound was prepared

출처 및 근거

ORD 기록
ord-e75fcf89300a4734a49db13fd7c93750
출처 데이터셋
uspto-grants-2015_02
특허 번호
US08946427B2

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