Hydrochloric Acid → HCID 86675624, compound

HRID 1844580Notes

Reaction equation

HRID 1844580 reaction equation
C[C@:2]1([CH2:18][CH2:19][CH2:20][N:21](C(OC(C)(C)C)=O)C(OC(C)(C)C)=O)[CH2:4][C@@:3]1([C:8]1[N:9]=[CH:10][N:11]([C:13]2[S:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=1)[C:5]([OH:7])=[O:6].[ClH:36]>>[ClH:36].[ClH:36].[NH2:21][CH2:20][CH2:19][CH2:18][C@H:2]1[CH2:4][C@@:3]1([C:8]1[N:9]=[CH:10][N:11]([C:13]2[S:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=1)[C:5]([OH:7])=[O:6]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 86675626HCID 86675626, compound

Product 1

HCID 86675624HCID 86675624, compound

Procedure

The compound (4.1 mg) obtained in Step 1 of this Example was heated to reflux for 3 hours in 5 N hydrochloric acid (3 mL). The reaction solution was concentrated under reduced pressure and then freeze-dried to obtain the title compound (2.6 mg).

Workup

  1. concentrationThe reaction solution was concentrated under reduced pressure
  2. customfreeze-dried

Sources & evidence

ORD record
ord-836b848848e44546bb2ea65cf1ceed3d
Source dataset
uspto-grants-2015_02
Patent number
US08946443B2

Reaction notes

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