HCID 58493959, compound → HCID 58493995, compound

HRID 1844599Notes

Reaction equation

HRID 1844599 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([N+:17]([O-])=O)[C:8]([O:15][CH3:16])=[C:9]([S:11]([CH3:14])(=[O:13])=[O:12])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2]>[Pd].CO>[C:1]([C:5]1[CH:10]=[C:9]([S:11]([CH3:14])(=[O:12])=[O:13])[C:8]([O:15][CH3:16])=[C:7]([CH:6]=1)[NH2:17])([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 1

HCID 58493959HCID 58493959, compound

Product 1

HCID 58493995HCID 58493995, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of 14.5 g 5-tert-butyl-1-methanesulphonyl-2-methoxy-3-nitro-benzene, 3.0 g 10% palladium on charcoal and 250 ml of methanol is shaken for 6 h at ambient temperature under a hydrogen atmosphere (50 psi). Then the catalyst is filtered off and the filtrate is evaporated to dryness.

Workup

  1. filtrationThen the catalyst is filtered off
  2. customthe filtrate is evaporated to dryness

Sources & evidence

ORD record
ord-7265cae222a148f29e47ddbf713a48a2
Source dataset
uspto-grants-2015_02
Patent number
US08946438B2

Reaction notes

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