HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → HCID 54704836, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | HCID 54687263 | HCID 54687263 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 54704836 | HCID 54704836 | 80% |
Reaction Steps
A mixture of 6-(tert-butyl)-4-hydroxy-2H-pyran-2-one (38 g, 168 mmol) and aq. NH4OH (150 mL, 30%) in dry toluene (200 mL) was heated at reflux for 1 h. The resulting mixture was concentrated and purified by CC (PE/EA=5/1) to give compound 17a (22.5 g, 80%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946446B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-3aa3da48cbfa4b77902b3f7462ee44d8 |
| Source note | uspto-grants-2015_02 |