Pentanoic Acid → HCID 86666375, compound

HRID 1844795Notes

Reaction equation

HRID 1844795 reaction equation
[C:1]([OH:7])(=[O:6])[CH2:2][CH2:3][CH2:4][CH3:5].[CH:8]#[C:9][CH2:10][NH:11][C@H:12]1[C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[CH2:14][CH2:13]1>C(OC(C)C)(C)C>[CH:8]#[C:9][CH2:10][NH:11][C@H:12]1[C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][C:15]=2[CH2:14][CH2:13]1.[C:1]([O-:7])(=[O:6])[CH2:2][CH2:3][CH2:4][CH3:5]

Participants

4

Reactant 2

HCID 7991Pentanoic AcidHCID 3052776Rasagiline

Product 1

HCID 86666375HCID 86666375, compound

Reagents, catalysts & solvents 1

HCID 7914Diisopropyl EtherSolvent2×

Procedure

To a solution of 60 mg (0.58 mmol, 1.0 eq) pentanoic acid in 0.5 ml diisopropyl ether a solution of 100 mg (0.58 mmol) rasagiline in 0.5 ml diisopropyl ether was added. After stirring for 90 min the solvent was removed in vacuo. The residue was dried in high vacuum for 5 h to yield a thick oil (158 mg, 0.58 mmol, quant.).

Workup

  1. customwas removed in vacuo
  2. customThe residue was dried in high vacuum for 5 h
  3. customto yield a thick oil (158 mg, 0.58 mmol, quant.)

Sources & evidence

ORD record
ord-5af47ff45e01472ea3ef14a180f17fff
Source dataset
uspto-grants-2015_02
Patent number
US08946482B2

Reaction notes

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