Trifluoroacetic acid → HCID 86700926, compound

HRID 1844850Notes

Reaction equation

HRID 1844850 reaction equation
[CH3:1][S:2]([CH2:5][CH2:6][NH:7]C(=O)OC(C)(C)C)(=[O:4])=[O:3].[F:15][C:16]([F:21])([F:20])[C:17]([OH:19])=[O:18]>ClCCl>[F:15][C:16]([F:21])([F:20])[C:17]([OH:19])=[O:18].[CH3:1][S:2]([CH2:5][CH2:6][NH2:7])(=[O:4])=[O:3]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 23061768HCID 23061768, compound

Product 1

HCID 86700926HCID 86700926, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In a dried reaction flask, tert-butyl 2-(methylsulfonyl)ethylcarbamate (0.906 g, 4.06 mmol) was dissolved in dichloromethane (60 mL). Trifluoroacetic acid (27.8 mL) was added dropwise at −10° C. The mixture was stirred for 1.5 hr, and was concentrated at reduced pressure to produce a crude brown oil (1.258 g).

Workup

  1. concentrationwas concentrated at reduced pressure

Sources & evidence

ORD record
ord-3f61ee972fec4422829219fc69d715a7
Source dataset
uspto-grants-2015_02
Patent number
US08946279B2

Reaction notes

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