Hydrochloric Acid → HCID 75530077, compound

HRID 1844857Notes

Reaction equation

HRID 1844857 reaction equation
[CH3:1][N:2]([CH3:15])[C@H:3]1[CH2:7][CH2:6][N:5](C(OCCCC)=O)[CH2:4]1.[ClH:16]>C(Cl)Cl>[ClH:16].[CH3:1][N:2]([CH3:15])[C@H:3]1[CH2:7][CH2:6][NH:5][CH2:4]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 86700927HCID 86700927, compound

Product 1

HCID 75530077HCID 75530077, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

In a dried reaction flask, the crude (S)-butyl 3-(dimethylamino)pyrrolidine-1-carboxylate (2.0 g) obtained in the above step was added to CH2Cl2 (30 mL). HCl gas was passed thereto for 3 hr. The solution was concentrated under reduced pressure to obtain a crude yellow viscous material (1.6 g).

Workup

  1. customIn a dried reaction flask
  2. concentrationThe solution was concentrated under reduced pressure

Sources & evidence

ORD record
ord-b91bd3ab96414501a96e55d1fb2bf404
Source dataset
uspto-grants-2015_02
Patent number
US08946279B2

Reaction notes

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