HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl 2-amino-1H-benzo[d]imidazole-4-carboxylate → 2-amino-6-pyridin-4-yl-1H-benzoimidazole-4-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl 2-amino-1H-benzo[d]imidazole-4-carboxylate | HCID 24730367 | — |
| Reactant | HCID 66940533 | HCID 66940533 | — |
| Product | 2-amino-6-pyridin-4-yl-1H-benzoimidazole-4-carboxylic acid methyl ester | HCID 66940503 | 50% |
Reaction Steps
0.25 g (50% overall yield) of 2-amino-6-pyridin-4-yl-1H-benzoimidazole-4-carboxylic acid methyl ester was synthesized according to procedures described for the synthesis of 2-Amino-1H-benzoimidazole-4-carboxylic acid methyl ester (intermediate A) starting from 0.5 g (1.8 mmol) of above synthesized 2-Amino-3-nitro-5-pyridin-4-yl-benzoic acid methyl ester. LCMS: 269 (M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08946259B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-984d841774e84e59b12b817a21bfc813 |
| Source note | uspto-grants-2015_02 |