Hydrochloric Acid → HCID 58188145, compound

HRID 1845254Notes

Reaction equation

HRID 1845254 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][N:14]=2)[CH:12]=1)[C:6]([O:8]C)=[O:7].O.O.O.O.O.O.O.O.[OH-].[Ba+2].[OH-].Cl>CO>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:10]=[C:11]([C:13]2[CH:18]=[CH:17][C:16]([CH3:19])=[CH:15][N:14]=2)[CH:12]=1)[C:6]([OH:8])=[O:7]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 17749109Barium hydroxide, octahydrateHCID 58188298HCID 58188298, compound

Product 1

HCID 58188145HCID 58188145, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Into a flask were charged methyl 3-methoxy-5-(5-methylpyridin-2-yl)benzoate (80 mg, 0.2 mmol), barium hydroxide octahydrate (300 mg, 0.95 mmol), and methanol (10 mL). The mixture was stirred at room temperature overnight. 2N HCl (ethyl ether solution, 30 mL) was added and the volatiles were removed under reduced pressure. LC-MS: 244.1 [M+1]+.

Workup

  1. customthe volatiles were removed under reduced pressure

Sources & evidence

ORD record
ord-7273d9d5e9d4445a9b14c2176a1e3226
Source dataset
uspto-grants-2015_02
Patent number
US08946439B2

Reaction notes

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