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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1845838Generated: October 31, 2026

5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine → HCID 60168622, compound

https://huagongshe.com/reaction/1845838

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amineHCID 21111478—
Reactant(4-Bromonaphthalen-1-yl)boronic acidHCID 23005424—
ReactantmethylphosphonoylmethaneHCID 178503022—
ProductHCID 60168622HCID 60168622—

Reaction Steps

The title compound was prepared from 5-bromo-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-2-ylamine, 1-bromo-4-(dihydroxyboryl)naphthalene, and dimethylphosphine oxide following the same procedures as Example 1 Step 1 and Step 3. ESMS: m/z 503 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08951993B2
Source datasetuspto-grants-2015_02
ORD IDord-dc40e2bda8cd4f41b384b8e84b5c630c
Source noteuspto-grants-2015_02