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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1845849Generated: October 29, 2026

5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine → HCID 60168718, compound

https://huagongshe.com/reaction/1845849

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amineHCID 21111478—
Reactant[4-Bromo-2-(trifluoromethoxy)phenyl]boronic acidHCID 54758858—
ReactantmethylphosphonoylmethaneHCID 178503022—
ProductHCID 60168718HCID 60168718—

Reaction Steps

The title compound was prepared from 5-bromo-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-2-ylamine, 4-bromo-2-trifluoromethoxyphenyl boronic acid, and dimethylphosphine oxide following the same procedures as Example 1 Step 1 and Step 3; ESMS: m/z 537 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08951993B2
Source datasetuspto-grants-2015_02
ORD IDord-e0cd673911904a329e2f4546bb590f1e
Source noteuspto-grants-2015_02