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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1845869Generated: October 30, 2026

1-(4-Amino-6-(methylthio)-1,3,5-triazin-2-yl)ethanol → 1-(4-Amino-1,3,5-triazin-2-yl)ethanol

https://huagongshe.com/reaction/1845869

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(4-Amino-6-(methylthio)-1,3,5-triazin-2-yl)ethanolHCID 67257933—
CatalystNickelHCID 935—
SolventEthanolHCID 702—
SolventWaterHCID 962—
Product1-(4-Amino-1,3,5-triazin-2-yl)ethanolHCID 6725607076.8%

Reaction Conditions

Temperature85 °C

Reaction Steps

To a solution of 1-(4-amino-6-(methylthio)-1,3,5-triazin-2-yl)ethanol (398 mg) in ethanol (20 mL) was added Raney nickel 50% slurry in water (6 mL) and the reaction mixture was heated to 85° C. for 30 minutes then cooled to room temperature, filtered and evaporated to give the title compound (230 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08952001B2
Source datasetuspto-grants-2015_02
ORD IDord-4e8caa51a2e446d591c607c667a83b3b
Source noteuspto-grants-2015_02