Hydroxide → 2-[[6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)pyridine-2-carbonyl]amino]-3,3-dimethylbutanoic acid

HRID 184597Notes

Reaction equation

HRID 184597 reaction equation
[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:24]3[CH2:25][C:26]([F:28])([F:29])[CH2:27]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[NH:14][CH:15]([C:16](=[O:17])[O:18][CH3:19])[C:20]([CH3:21])([CH3:22])[CH3:23])[n:11]2)[CH2:2][CH2:3]1.[Li+:30].[OH-:31]>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:24]3[CH2:25][C:26]([F:28])([F:29])[CH2:27]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[NH:14][CH:15]([C:16](=[O:17])[OH:18])[C:20]([CH3:21])([CH3:22])[CH3:23])[n:11]2)[CH2:2][CH2:3]1

Participants

4

Reactant 3

HCID 961HydroxideHCID 28486Lithium ionHCID 71087807Methyl 2-[[6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)pyridine-2-carbonyl]amino]-3,3-dimethylbutanoate

Product 1

HCID 710877742-[[6-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)pyridine-2-carbonyl]amino]-3,3-dimethylbutanoic acid

Sources & evidence

ORD record
ord-7ab1707f20e94d5ab6cded191e257d3d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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