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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846092Generated: November 2, 2026

2-Chloro-5-[(2,2-dimethylpropanamido)methyl]benzoic acid → HCID 86658672, compound

https://huagongshe.com/reaction/1846092

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-5-[(2,2-dimethylpropanamido)methyl]benzoic acidHCID 58483208—
ReactantHCID 58483478HCID 58483478—
SolventTetrahydrofuranHCID 8028—
ProductHCID 86658672HCID 86658672—

Reaction Steps

Prepared analogously to Example 2f from N-(4-bromophenyl)-2-(2,2-difluoroethyl)oxy-5-amino-nicotinic acid amide and 2-chloro-5-(tert-butylcarbonylamino)methyl-benzoic acid with PPA and TEA in THF. Purification via HPLC (Method A)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08951999B2
Source datasetuspto-grants-2015_02
ORD IDord-cfc3f754fde543af9841c834cf974eae
Source noteuspto-grants-2015_02