HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) → HCID 52919967, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1) | HCID 9886157 | — |
| Reactant | HCID 58483224 | HCID 58483224 | — |
| Reactant | HCID 58483373 | HCID 58483373 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 52919967 | HCID 52919967 | — |
Reaction Steps
Prepared analogously to 43b from 2-chloro-3-(tert-butylcarbonylamino-methyl)-6-fluoro-benzoic acid and 5-amino-N-(4-bromo-phenyl)-2-(2,2-difluoro-ethoxy)-benzamide with HATU and TEA in THF.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08951999B2 |
| Source dataset | uspto-grants-2015_02 |
| ORD ID | ord-3fadcd2041fa461e88a3e767c2a2f972 |
| Source note | uspto-grants-2015_02 |