Hydrochloric Acid → 7-{4-[4-(1-Methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-8-yl)-piperazin-1-yl]-butoxy}-3,4-dihydro-1H-[1,8]naphthyridin-2-one

HRID 184611Notes

Reaction equation

HRID 184611 reaction equation
[CH3:2][N:3]1[C:4](=[O:19])[CH2:5][CH2:6][c:7]2[cH:8][cH:9][cH:10][c:11]([N:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[c:12]21.[ClH:1].[O:20]=[C:21]1[CH2:22][CH2:23][c:24]2[cH:25][cH:26][c:27]([O:31][CH2:32][CH2:33][CH2:34][CH:35]=[O:36])[n:28][c:29]2[NH:30]1>>[CH3:2][N:3]1[C:4](=[O:19])[CH2:5][CH2:6][c:7]2[cH:8][cH:9][cH:10][c:11]([N:13]3[CH2:14][CH2:15][N:16]([CH2:35][CH2:34][CH2:33][CH2:32][O:31][c:27]4[cH:26][cH:25][c:24]5[c:29]([n:28]4)[NH:30][C:21](=[O:20])[CH2:22][CH2:23]5)[CH2:17][CH2:18]3)[c:12]21

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 210732001-Methyl-8-piperazin-1-yl-3,4-dihydroquinolin-2-oneHCID 210733774-((7-Oxo-5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)oxy)butanal

Product 1

HCID 210734967-{4-[4-(1-Methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-8-yl)-piperazin-1-yl]-butoxy}-3,4-dihydro-1H-[1,8]naphthyridin-2-one

Sources & evidence

ORD record
ord-115b60eb942f44e89b65b630245a1baf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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