HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1846370Generated: November 2, 2026
tert-Butoxy bis(dimethylamino)methane → HCID 86659823, compound
https://huagongshe.com/reaction/1846370
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | tert-Butoxy bis(dimethylamino)methane | HCID 79885 | — |
| Reactant | HCID 86659822 | HCID 86659822 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 86659823 | HCID 86659823 | 95.4% |
Reaction Steps
tert-Butoxybis(dimethylamino)methane (2.0 mL, 9.60 mmol) was added to a solution of 3-(4-bromophenyl)-2-(3-methyl-4-nitrophenyl)quinazolin-4(3H)-one (1.4 g, 3.20 mmol) in DMF (30 mL). Stirring at 60° C. for 2 hours and concentrating in vacuo afforded (E)-3-(4-bromophenyl)-2-(3-(2-(dimethylamino)vinyl)-4-nitrophenyl)quinazolin-4(3H)-one (1.5 g, quantitative).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08952021B2 |
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| Source dataset | uspto-grants-2015_02 |
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| ORD ID | ord-e5f9ba905d0c4b36a1b1f408ad72ce47 |
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| Source note | uspto-grants-2015_02 |
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