Hydrogen Peroxide → 6-hydroxy-4-methylbenzo[d]oxazol-2(3H)-one

HRID 1846417Notes

Reaction equation

HRID 1846417 reaction equation
[CH3:1][C:2]1[C:7]2[NH:8][C:9](=[O:11])[O:10][C:6]=2[CH:5]=[C:4]([O:12]B(O)O)[CH:3]=1.OO>C(O)(=O)C>[OH:12][C:4]1[CH:3]=[C:2]([CH3:1])[C:7]2[NH:8][C:9](=[O:11])[O:10][C:6]=2[CH:5]=1

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 669782724-Methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-6-ylboric acid

Product 1

HCID 669780936-hydroxy-4-methylbenzo[d]oxazol-2(3H)-one

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

77 mg (0.40 mmol) 4-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-6-ylboric acid were dissolved in 2.0 mL glacial acetic acid and mixed with 0.20 mL (2.3 mmol) hydrogen peroxide solution (35% in water) and stirred briefly. The reaction mixture was left to stand for 1 h at RT. The precipitate formed was suction filtered, washed with water and dried i. vac.

Workup

  1. waitThe reaction mixture was left
  2. customThe precipitate formed
  3. filtrationfiltered
  4. washwashed with water
  5. customdried i

Sources & evidence

ORD record
ord-ae0a62c06edc422f8e8d1e65b131a93d
Source dataset
uspto-grants-2015_02
Patent number
US08952014B2

Reaction notes

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