HCID 5135648, compound → HCID 66978206, compound

Participants

Reaction Steps

A mixture of 45.0 g (0.188 mol) N-(2-methyl-4,6-dinitro-phenyl)-acetamide and 4.50 g palladium on charcoal (Pd/C 10%) in 1.400 L methanol was hydrogenated for 2 h at RT under a hydrogen atmosphere. The catalyst was removed by suction filtering and the filtrate was evaporated to dryness i.vac. The residue was triturated in diethyl ether, suction filtered and dried. The crude product obtained was used directly for the next step.

Provenance & Evidence