HCID 66978206, compound → HCID 66978194, compound

Participants

Reaction Steps

33.0 g (0.184 mol) N-(2,4-diamino-6-methyl-phenyl)-acetamide were stirred in 400 mL glacial acetic acid for 1.5 h at 100° C. The glacial acetic acid was eliminated i.vac. and the residue remaining was triturated with ether, suction filtered and dried. The free base thus obtained was taken up in methanolic hydrochloric acid and left to stand. The hydrochloride slowly settling out as a precipitate was suction filtered, washed with acetone and dried.

Provenance & Evidence