4,6-Dichloropyrimidine → HCID 86663897, compound

Participants

Reaction Conditions

Reaction Steps

300 mg (1.70 mmol) 6-amino-3,4-dimethyl-3H-benzoxazol-2-one, 276 mg (1.90 mmol) 4,6-dichloropyrimidine and 0.77 mL (60 μmol) TEA were combined in 5.0 mL 1-butanol and the mixture was stirred for 1 h at 100° C. The reaction mixture was cooled to RT, evaporated down and the residue was triturated in diethyl ether. The precipitate was washed with water and dried i. vac.

Provenance & Evidence