Acetic Anhydride → HCID 86663901, compound

Participants

Reaction Conditions

Reaction Steps

100 mg (0.300 mmol) 6-(6-chloro-pyrimidin-4-ylamino)-3,4-dimethyl-3H-benzoxazol-2-one were placed together with 1.00 ml (10.6 mmol) acetic anhydride in a microwave container and stirred for 20 min at 150° C. The reaction mixture was diluted with water and extracted with DCM. The organic phase was separated off, dried and evaporated down. The residue was purified by preparative HPLC. The product-containing fractions were combined and evaporated down.

Provenance & Evidence